The four management functions in relation to operation management Essay

The four management functions in relation to operation management theory - Essay Example The paper tells that there are four functions that a manager accomplishes in a business organization. These four functions are known as planning, controlling, organizing, and leading. This section of the paper will look at these individual functions closely. Planning involves the "ongoing process of developing the business' mission, and objectives, and how they will be accomplished." The planning process can be used in a broad sense to take into account the whole organization. This will include devising the company's mission and vision. It can also be applied in a specific situation such as the formulation of a strategy to increase the company's market share. Organizing, on the other hand, refers to the creation of the company's organizational structure. This involves determining the functions to be done as well the resources to accomplish them. Organizing also includes how processes will be managed and coordinated. In summary, the organizing function encompasses how managers distrib ute tasks to job holders and focus on division of labor, coordination, control of tasks, and flow of information within the organization. The third managerial function is leading to other writers refer to this function as directing. Leading "is influencing people's behavior through motivation, communication, group dynamics, leadership, and discipline." The real essence of leading is for the manager to equip the employees with their needs to realize the organization's objectives while giving them room to achieve their respective career objectives. Controlling is the managerial function which necessitates the identification of the company's specific goals. Controlling is a "four-step process of establishing performance standards based on the firm's objectives, measuring and reporting actual performance, comparing the two, and taking corrective or preventive action as necessary." Put simply, the controlling function of management is the check and balance system which tries to reveal th e inefficiencies in the strategies employed in realizing the goals of the organization. Controlling is very significant as it tells the managers the loopholes and enables them to correct their systems in order to enhance the company's performance. The operation is one of the functional areas of an organization. Operations management is essentially the area which carefully manages the processes of the company's value chain in order to efficiently produce and distribute its products and servicesÃ'Ž Operations management is indispensable in the functioning of any business organization may it be a small start-up entity or a large manufacturing firm. Operations management deals with the management of the company's core activity. Therefore, the functions of operations managers vary with the major activity of a business entity. The operation manager of a company engaged in the manufacture of children’s toys is basically tasked to oversee the firm’s value chain from the procu rement of raw materials, assembly, sales, and after sales services such as handling of complaints and warranties. On the other hand, the operations managers of a service company like a spa handles day to day activities like management of workforce to service the customers.

Role Of Women In Ancient Egypt Essay Example | Topics and Well Written Essays - 250 words

Role Of Women In Ancient Egypt - Essay Example Hatshepsut reigned until her death in 1457 B. C, despite the constant threat by her co-ruler Thutmose III, who was at the time old enough and ready to take back his throne. Upon her death, most of her monuments were destroyed, and her name erased from the Egyptian records. Ancient Egyptians were religious, and women had several roles to play in religious activities. First, there were several female goddesses worshiped by the Egyptians. Women were also musicians and priestesses in the temples where religious ceremonies were held. In the role of the temple, women were musician-priestesses and held an important and honorable place in Egyptian religious society. They performed music and sung for the god Amum for his entertainment. In the social role, women were supposed to offer companionship and love to the Egyptian men. They also held the role of childbirth. During child delivery, other women acted as midwives to help the expectant woman through the whole process. Women were also responsible for the raising up of the children. Economically, women were allowed to start and run businesses of their own. In addition to this, several jobs were available to them. They included perfume makers, bakers, and weavers among others (Flux 19). To sum it up, in ancient Egypt, unlike other ancient societies, women were given same legal and economic right. Women were allowed to own, manage and even sell their private properties. Through building projects, Hatshepsut ensured the divine property of both herself and her people.

The Five Dysfunctions of a Team Essay Example | Topics and Well Written Essays - 1250 words

The Five Dysfunctions of a Team - Essay Example Decision Tech’s employs too could not work together efficiently, they could not create their own magnetism because ‘†¦ few key employees below the executive level unexpectedly left the company. Morale deteriorated†¦Ã¢â‚¬â„¢ if this technological company had learnt the attributes of team work, they needed not to have depended on Jeff Shanley leadership ‘.. Someone had to be accountable for the mess, and Jeff was the man at the top.’ The big attribute of team work revolves around cheering and bolstering their leader, this lacked in this firm instead Decision Tech developed a reputation within the valley for being one of the most political and unpleasant places to work. Question two: Review the information on the establishment of team â€Å"Norms† during the forming and norming stages of team development in your text on pages 498 -501. What behavioral norms had been established by the executive team at Decision Tech before Kathryn took over? How did these norms help or hurt the company’s performance? Dependence and superficiality: There was little interaction which was formal or guarded, in establishing clarity of purpose, norms, procedures and expectations thus cohesive unit could not be created. The more employees interact together the more they develop a common behavior. This lacked in Decision tech’s capacity leading to a poor performance There was a lot of cooperativeness and heightened interpersonal attraction‘†¦ it had the most experienced – and expensive- executive team imaginable†¦Ã¢â‚¬â„¢ this helped it a lot to attract even the ‘†¦cautious venture ï ¬ rms†¦Ã¢â‚¬â„¢ who were ‘†¦ lining up to invest, and talented engineers were submitting their rà ©sumà ©s before the company had leased even an office.’ The firms employees conformed to standards and expectations for high achievement leading to ‘†¦a seemingly indestructible business plan and more top-tier

Marketing For Non-profit Organizations Case Study

Marketing For Non-profit Organizations - Case Study Example Coming to the Political factors which can influence the museum, it was identified that the Mayor's commission on the inclusion of Asian and African settlers in London into the Heritage could play an instrumental role in deciding if the museum would get the required support from the Greater London Association (GLA) for its further needs. It could also play a role in making a political impression, which could go a long way in the museum's growth. The 2012 Olympics and its preparations were also taken into consideration while formulating the political factors. At this juncture when the Government of UK was looking forward to make rapid changes to the city of London in a big way and also promote tourism, it is an undisputable fact that the museums would directly be impacted from this move. The 2012 Olympics and the Government's preparations for it and also the modernization agenda of London would really help the museum sector in the long run. Likewise, the social factors were identified to be the literacy rate of the city, country and the constitution of the population. Around 28% of the population consisted of the Asians and Africans and it was clearly identified that there was a need to include and appreciate their services too. Hence, extensive SWOT and PEST analyses on the British museum and the museum sector as a whole and suggestions were made. Since the marketing audit is essentially divided into Internal and External m arket analyses, we classify strengths, weaknesses as the internal analysis of the museum. Likewise, we classify political, economic, social and technological factors as the external environmental condition for any organization. It is obvious that the external environment for the museum too plays a crucial role in the growth of the organization in the long run. Marketing Audit and Recommendations It is a well-known fact that the British museum in London is one of the world's greatest museums of human history and culture. Its collections, which number more than 13 million objects from all continents, illustrate and document the story of human culture from its beginning to the present. is a point of controversy whether museums should be allowed to possess artefacts taken from other countries, and the British Museum is notable target for criticism (Albert Gunther, 2003).The Elgin marbles and the Benin Bonzes are among the most disputed objects in its collections, and organisations have been formed demanding the return of both sets of artefacts to their native countries of Greece and Nigeria respectively. The British Museum has refused to return either set, or any of its other disputed items, stating that the "restitutionist premise, that whatever was made in a country must return to an original geographical site, would empty both the British Museum. The Museum has also argued th at the British Museum Act of 1963 legally prevents it from selling any of its valuable artefacts, even the ones not on display. Internal Environment Analysis The Weaknesses Lack of funds, has clearly paralyzed the prospects of development of the museum in a real big way. Under funding has clearly caused discontent among the employees of the organization. In fact there were instances when the employees had gone off their duties in order to protest the government's attitude towards the museum. At a time when

All information is in the document, Essay Example | Topics and Well Written Essays - 1750 words

All information is in the document, - Essay Example the main features in the film is that is characteristic of an urban setting is the firearms that are used in the action and bloodshed combats in the plot of the film. In a rural Asian setting, the main weapon to combat enemies was the sword. This is what is used in most Asian action traditional movies and the martial arts of Tai Kwando are employed. In this film however, modern firearms with live bullets are used in the action scenes. These are cocked and fired by pulling the trigger which gives the film an all modern aura. Another element of modern setting in the film was depicted with the occupation of Sung Tse-Ho. Ho’s principle job was printing and distributing fake bank notes of the US dollars. The fact that printing in itself was done is a very modern element. Traditionally primitive forms of writing were the only forms of permanently inscribing information on a piece. The bank notes also implied that the main form of exchanging goods and services or for trading was monetary which is different from the traditional barter trading system. In addition to that it depicts the presence banks in the film setting which are only characteristic of modern settings. Very few rural settings have a bank anywhere in the vicinity. This made a great impact in the lives of the dwellers and visitors of the area. They got to enjoy the services associated with banking such as borrowing of loans, keeping money safely in a personal account, saving money through savings accounts that earn interest and the like. T he dwellers and visitors also got job employments that are associated with banks such as being bank tellers, being bank watchmen and women and being cleaners. The younger brother of Ho, Kit, aspired to be a policeman. This is an influence that he got as a dweller of an urban setting. Policemen are a typical feature of an urban setting. They mascaraed the streets in their uniforms with some even holding gins or pistols. These are likely to look cool for a young man

About the Future Essay Example for Free

About the Future Essay Basic research will show that legalizing this plant can benefit our country whether you smoke it or not. A simple lesson in supply and demand will show that legalizing marijuana would create a significant drop in price due to the elimination of the risk factors of growing and also selling paraphernalia. When the alcohol prohibition ended, the price dropped to a third of its prohibition cost. A study done by the Task Force on Cannabis Regulation to the Center for the Study of Drug Policy-Regulation and Taxation of Cannabis Commerce reveals that legalization could open up a tax revenue stream for governments. Licensing, taxing, and fees could generate up to 7 billion dollars a year not including the taxes on sales of paraphernalia, recreational establishments and new industries according to a study by the Congressional Budget Office with state sales tax being the factor in determining basic revenue In 1972, after reviewing the scientific evidence, the National Commission on Marihuana and Drug Abuse concluded that while marijuana was not entirely safe, its dangers had been grossly overstated. Since then, researchers have conducted thousands of studies of humans, animals, and cell cultures. None reveal any findings dramatically different from those described by the National Commission in 1972. In 1995, based on thirty years of scientific research editors of the British medical journal Lancet concluded that the smoking of cannabis, even long term, is not harmful to health. Marijuana is a good medicine for sick patients therefore it should be legalized because most patients say that marijuana helps them feel better. For example, patients use marijuana to fight symptoms caused by their sickness. Doctors and nurses all had patients who had used marijuana to fight nausea and who have reported good results. That is saying that marijuana is an effective way to help fight off bad symptoms. Marijuana is a good medicine to help get rid of bad feelings. Drug education and prevention programs reduced marijuana use during the 1980s. Since then, our commitment has slackened, and marijuana use has been rising. By expanding and intensifying current anti-marijuana messages, we can stop youthful experimentation. There is no evidence that anti-drug messages diminish young peoples interest in drugs. Anti-drug campaigns in the schools and the media may even make drugs more attractive. Marijuana use among youth declined throughout the 1980s, and began increasing in the 1990s. This increase occurred despite young peoples exposure to the most massive anti-marijuana campaign in American history. In a number of other countries, drug education programs are based on a harm reduction model, which seeks to reduce the drug-related harm among those young people who do experiment with drugs. Cigarettes and alcohol are more dangerous than marijuana, which it should be legalized. A lot of research has been done to prove it. Cigarettes are horrible for health and alcohol causes many bad things to happen. This quote shows how marijuana is less harmful then tobacco and alcohol. Experts do believe that moderate marijuana use is relatively less harmful to the user than either tobacco or alcohol. Cigarettes and alcohol are legal and cause more of health problem then marijuana. Moderate smoking of marijuana appears to pose minimal danger to the lungs. Like tobacco smoke, marijuana smoke contains a number of irritants and carcinogens. But marijuana users typically smoke much less often than tobacco smokers, and over time, inhale much less smoke. As a result, the risk of serious lung damage should be lower in marijuana smokers. There have been no reports of lung cancer related solely to marijuana, and in a large study presented to the American Thoracic Society in 2006, even heavy users of smoked marijuana were found not to have any increased risk of lung cancer. Unlike heavy tobacco smokers, heavy marijuana smokers exhibit no obstruction of the lungs small airway. That indicates that people will not develop emphysema from smoking marijuana. Marijuana is a remarkably safe and non-toxic drug that can effectively treat about 30 different conditions, he tells Web MD. I predict it will become the aspirin of the 21st century, as more people recognize this.

The Biopharmaceuticals An Overview Biology Essay

The Biopharmaceuticals An Overview Biology Essay Biopharmaceuticals are defined as proteins and nucleic acids which are used for therapeutic purpose. These are high molecular weight substances prepared by biotechnological means and genetically engineered. Due to their complex structure and intricate molecular composition it is very difficult to characterize and formulate such products. Most of these products are derived from biological species and genetically engineered to produce a potent compound [1-3]. Humulin (biosynthetic recombinant human Insulin) was the first biopharmaceutical product developed by Genentech but licensed and marketed by Eli Lily and Company in 1982. In the modern era biopharmaceutical products have become a major facilitating reason of technological changes in health care sector, causing extraordinary benefits for patients, cost challenges for consumers, and profits for market shareholders.[4] Over the last decade biopharmaceutical market is the fastest growing segment in the pharmaceutical organizations. After post-recession period vigorous advancement has been seen in this area. It has been reported that approximately 40% of total pharmaceutical RD investment is occupied by biopharmaceutical products amongst which, monoclonal antibodies and product produced by recombinant DNA method are the most prevalent one.[5,6] Proteins with different amino acid sequences are the primary structure of such products. For determining the biological activity of a protein it is necessary to study its three-dimensional structure. The structure of protein is generally divided into four categories i.e. primary, secondary, tertiary and quaternary (fig. 1). The primary structure is the sequence of amino acid residues which folds and stabilized by the formation of hydrogen bonds with subsequent molecules in the polypeptide chain to produce an  ÃƒÅ½Ã‚ ± helix,  which is a spiral, rod-like st ructure, or a  ÃƒÅ½Ã‚ ² sheet,  a planar structure. This structure resembles to the secondary structure of proteins. The tertiary structure is a three-dimensional arrangement which gives an overall conformation of a polypeptide chain. Through hydrophobic interactions between the non-polar side chains and disulfide bonds, this tertiary structure is stabilized. A quaternary or multimeric protein contains two or more polypeptide chains, held together by non-covalent bonds.[7] fig 1. Structure of protein. Because of their unique physicochemical characteristic it is very hard and challenging to formulate biopharmaceuticals as products with therapeutic effects and storage characteristics. Meanwhile their formulation is in many ways different from conventional low-molecular drug formulation. Despite of such facts biopharmaceuticals gains lots of attention in the modern era of drug formulation. In the recent reviews it has been discussed that around 400 biotechnology-based medicinal and therapeutic agents are either registered or in the clinical trials are reviewed by the regulatory bodies. These agents are helpful in treating many life threatening diseases some of them are cancer, infectious diseases, autoimmune diseases, and AIDS/HIV. Some of the agents which are already in the market are monoclonal antibodies, recombinant hormones, cytokines, vaccines, recombinant blood factor, and therapeutic enzymes.[5] Discussion Biopharmaceutical market In 1970, discovery of recombinant DNA technology and monoclonal antibodies lead to initiate the development of biopharmaceutical industries. A substantial growth from $8 billion in 1992 to $149 billion in 2010 quenched the thirst of investors towards the biopharmaceutical industry. It is expected to reach $239 billion by 2015 with a growth rate of 9.9% annually. There are more than 400 Biotech drugs and vaccines are scrutinized under clinical stage, targeting more than 200 diseases. Meanwhile a large number of the population is now taking benefits from a number of biotechnological innovations like recombinant protein-based products e.g. monoclonal antibodies and some large molecule prescription drugs, which include hormones and vaccines. Table 1 illustrates some of the leading biopharmaceutical therapy classes by size worldwide in 2002. In 2008 approximately 39%, among the top 10 drugs sold globally, are biopharmaceuticals and is expected to rise to 79% of the top 10 drug sales by 20 14.[8] Table.1: Leading biopharmaceutical therapy classes by size worldwide 2002. Source: IMS MIDAS December 2002. However after the post recession period, fundings over health care and other sector is reduced which impede the growth rate of pharmaceutical industries up to significant extent. Although biopharmaceutical global sales thrive to attain high numbers in the global health sector. Biotechnological based products have generated $229 billion revenue in 2012 with an annual growth rate of 10.4%. Meanwhile the major focus of pharmaceutical organizations is on biopharmaceutical vs. Small molecule drugs which enables to allocate high funding towards this area. This may be due to very less generic biosimilar products available in the market. In year 2009 there are total 18 biopharmaceutical products are approved by US FDA which is higher than the previous years i.e. 11 in 2008 and 10 in 2007. In a report of Battelle Technology Partnership Practice, it was estimated that the overall impact of biopharmaceutical sector on the US economy is $917 billion. These companies are making alliances with oth er essential services such as computing and information, clinical trial and regulatory support services, technologies, manufacturing and equipment, and transportation and logistics providers.[9-11] Types of Biopharmaceuticals Cytokines Cytokines are a diverse group of non-antibody intercellular signalling regulatory proteins i.e. glycoprotein and low molecular weight peptides produced in very little amount inside the body. They function as a mediator for communication between various cells and induce certain response by binding to specific cell surface receptors which results in triggering various intracellular signal transduction mechanism. There are over 80 sub class of cytokines have been found. Some of these are categorized in table 2. They play an important role in coordinating embryonic development, cell growth and maturation, wound repair and healing, the immune response including acute phase reactions and septic shock, and new blood vessel formation. Cancer is among the major class of disease which is thoroughly scrutinized by the researchers with an emphasis on cytokines. However cytokines also play a vital role in mediating signalling response to systemic inflammation which tends to regulate specific neur onal network to induce sickness. Some animal studies reveal the role of cytokines in situations characterized by abnormal sleep, with emphasis on the pathogenesis of symptoms and consequences of OSAS (Obstructive sleep apnoea syndrome). Cytokines interact with specific cells via (1) intracrine, in which both cytokine and receptor remain within the cell (rare); (2) autocrine, where a cytokine acts on the receptors of the same cell it is produced; and (3) paracrine, where the cytokine from one cell type interacts with receptors on other cell types.[12-16] Table 2: categorization of cytokines. There are various cytokines products available in the market and some of them are reviewed under the clinical phase for example Interleukin-2 (IL-2) aldesleukin (Proleukin), for treating renal cell carcinoma is approved by FDA. IL-1 blocker, anakinra (Kineret) and rilonacept (Arcalyst) are used for the treatment of rheumatoid arthritis and cryopyrin-associated periodic syndromes respectively.[1] Enzymes Enzymes are complex molecules produced by living cells. They increase the rate of chemical reaction without even showing their own effect in the process and hence act as a catalyst in living organisms.[17] Because of their reaction specificity, catalytic efficiency and ability to operate under mild condition of temperature and hydrogen ion concentration they are preferred as a novel class of therapeutic agents. Despite of their therapeutic role enzyme endures significant importance as a replacement therapy in many genetic disorders. However there are some disadvantages as well associated with their use such as, their parental administration required extensive purification to remove contaminants. They are also very costly to prepare and due to their large molecular structure they have limited distribution in the body. As they are proteins hence when administered inside the body act as antigen to the host cell.[18,19] Enzymes are categorized under six major classes i.e transferases, lysases, hydrolases, isomerases, ligases, and oxidoreductases. The potential utility of enzyme as pharmaceutical was noted many decades ago. However most of the enzyme therapies are used to treat functional defects. Activase ® (alteplase; recombinant human tissue plasminogen activator), is the first recombinant enzyme drug which was approved by the Food and Drug Administration in 1987. Pulmozyme ® (Dornase alpha), a recombinant DNAse I that digests DNA in the mucous secretions in lungs, used to treat cystic fibrosis. Adagen ® (pegadamase bovine), is the first marketed product as enzyme therapy for the treatment of SCID (severe combined immunodeficiency disease).[20] Hormones Hormone is characterized as an important group of regulatory molecule which is synthesized in an organ or in tissue and then secreted into circulatory system where it affects respective organs whose cell bears an appropriate receptors. They are chemical messengers either small or a large macromolecule and are fairly defined as endocrine hormones. Approximately all endocrine hormones possess therapeutic importance and hence subsequently used by the researchers e.g. insulin(Insugen ®, Humulin ®, Novolin ®), human growth hormone (Ascellacrin ®, Crescormon ®), glucagon, and the gonadotrophins.[1] Antibodies: Antibodies or immunoglobulin are proteins produced, as an immune response, through white blood cells when a foreign particle or antigen intrudes inside the body. There are five classes of immunoglobulin IgE, IgM, IgG, IgD, and IgA. Amongst them IgG is the most common as a biopharmaceutical agents. A more specified term i.e. monoclonal antibodies (mAb  or  moAb) are the novel class compounds that are first developed in mid 1970s by kohler and Milstein, who successfully fused immortal cells with antibody- producing B lymphocytes. This fusion results in a hybrid which is stable, cancerous, antibody- producing cells. These are referred as hybridoma cells which unveil great source of monoclonal antibody. mAb identify antigens on a particular foreign body very specifically. mAbs are categorized under four groups according to their source: murine (derived solely from mice), chimeric (mixture of murine and human sequences), humanised (contain over 90% human sequences) and fully human.[8, 17] In 1986, Murobmonab (OKT3), a murine antibody, is the first monoclonal antibody tested as a therapeutic in humans. However it fails to produce a substantial response in the transplantation rejection patients because of production of anti-murine antibody.[20] Monoclonal antibodies are the fastest growing therapeutic class in the field of biopharmaceutical market. The market of monoclonal antibodies crosses the mark of $30 billion in 2011. Infliximab (Remicade) is the top selling monoclonal antibody in 2002 which was developed by Centocor and is marketed by Centocor and Schering-Plough for the treatment of rheumatoid arthritis (RA) and Crohns disease. Rituximab (Rituxan), developed by Genentech and IDEC and marketed by Genentech, IDEC and Roche, for the treatment of non-Hodgkins lymphoma, is the second largest selling monoclonal antibody.[21] Vaccines: Vaccines are antigenic proteins which are either partial or modified form of bacteria, viruses and toxins which causes certain diseases against which vaccine protects. The antigenic property of vaccines is altered from its original form by certain processes such as utilizing attenuated viruses, inactivated viruses, part of a virus or bacteria and toxin produced by bacteria; hence they lack ability to cause disease although, endures ability to produce an immune response.[22] Vaccines are the only known prophylactic approach which are commonly available to cure many infective diseases. Vaccines cover the global market share of $ 3 billion annually. Government health agencies run different immunization programs which alleviate the risk of many infective disorders. However, there are approximately 15 million people die every year from certain infectious diseases that can be cured by vaccination process. Pharmaceutical and biopharmaceutical industries seek great potential in this area but the use is limited because of their high production cost, delivery and distribution problems. Vaccines may contain animal derived products such as Bovine serum albumin or fetal calf serum or human derived product for example using cell lines of human tissues. However in recent years transgenic and recombinant plants are also utilized for the production of vaccines.[12,23,24] There are different vaccines available in the market for many infectious diseases such as poliomyelitis, cholera, diphtheria, tetanus, hepatitis B, hepatitis A, measles, meningitis etc. For hepatitis B virus some examples are Baraclude (Entecavir ®), Adefovir dipivoxil (Hepsera ®), Lamivudine (Epivir ®-HBV, 3TC), Alfa Interferon (Intron ® A, Infergen ®, Roferon ®).[1,25] Antisense drugs: Antisense compounds are non-coding strand of messenger RNA(mRNA), which hybridize with mRNA and inactivates the ability of genes to produce the protein for which it holds the recipe.[26] They do not alter human gene causing variation in human genetic information. It was first developed in 1978 using a string of DNA nucleotide which binds with messenger RNA and block its function. These drugs are designed to treat a wide range of diseases such inflammatory, infectious, cancer and cardiovascular diseases. Fomiversen was the first antisense drug approved in 1998 for the treatment of cytomegalovirus retinits in AIDS patients. These are categorized under three sub-classes i.e. antisense oligonucleotides(ASONs), ribozymes and RNA interference(RNAi). Affinitak, manufactured by ISIS pharmaceuticals and Eli Lilly, is used for the treatment of non-small-cell lung carcinoma(NSCLC). There are certain antisense compound are under review by health agencies for their therapeutic efficacy towards ma ny anomalies[27,28] Peptide therapeutics: Peptides are polymers having one or two amino acids linked with amides and are chemically synthesized by using liquid phase or solid phase synthesis. Their chemical synthesis is preferred over biosynthetic approach because it facilitates the conjugation or incorporation of small molecules and non-natural amino acids. This approach reveals the potential of such molecules as cytotoxic agents for antitumor therapy. Peptides with non-natural opens up the possibility for greater chemical diversity, analogous to small-molecule medicinal chemistry approaches for developing high-af ¬Ã‚ nity, highspeci ¬Ã‚ city molecular recognition. Cationic antimicrobial peptides (CAMPs) and peptidoglycan recognition proteins (PGRPs)are developed from the effectors of innate immune response in eukaryotes during their defense mechanism. However there are not many products of peptides found in the market but researchers are trying to develop some therapeutic peptides and proteins with significant effect towards certain diseases. Nesiritide (Natrecor, Noratak) is produced by Johnson Johnson2001, Teriparatide (Forteo) is developed and marketed by Lily in 2002 Enfuvirtide (Fuzeon) is manufactured by Trimeris 2003.[29-31] Challenges associated with biopharmaceutical products: Biopharmaceutical products such as monoclonal antibodies, vaccines, certain hormones, and cell therapies are rewarded as some of the most promising innovation in the field of medicine and health. However there are certain risk and challenges associated with such products which hamper their performance. One of the major challenges is the purification of proteins although it can be achieved by various processes but still purification of such compound is very critical hence requires a lot of attention during manufacturing. Next generation pharmaceutical.[32] However the whole process is carried out under two phases i.e. upstream and downstream regulation. Immunogenicity associated with some of these proteins is also a major concern for biopharmaceutical agents. A repeated injection of human protein may affect the immune tolerance towards self- antigen, leading to humoral response.[33]   Biopharmaceutical products require greater attention, process level as well as monitory level, in the development phase of the drug discovery process it requires approximately $200 million to develop a biopharmaceutical product hence the risk associated with their failure during development stage is increased. Apart from purification and immunogenicity some other issues also make some impact during their development such as government regulations which influence the cost of such products. As discussed earlier it takes a large amount of money to develop such agents hence companies also compensate their development cost and earn profits from their products, ones marketed, which exponentially increases the cost of the drugs. Last and one of the most important risk associated with such products is the introduction of biosimilar products. Biopharmaceutical market is growing very fast, the initial compounds of the first generation are now coming to an end. The expiry of the patents opens the market for generic products which not only influence the established market of some very popular brands, it also forms a milieu of competition to sell the products at cheaper rates which is compensated by their quality.[34] Conclusion Biopharmaceutical products are one amongst the novel class of therapeutic compounds. These are medical agents obtained from biological sources and some special one are manufactured by biotechnological means. They are cellular products, therapeutic proteins, vaccines, gene therapy products and plasma blood product derivatives. Erythropoietins, insulins, and monoclonal antibodies, are some of the leading biopharmaceutical products available in the market hence biopharmaceutical companies are now focusing on their use in long-term conditions such as cardiovascular disease, diabetes and asthma. The blockbuster sales of some existing biopharmaceutical products accompanied by the tremendous innovation and a plethora of pipeline products demonstrate the vigorous growth in the biopharmaceutical market in upcoming years. This significant growth is supported by some of the key segments of the field like monoclonal antibody and vaccines. In addition approaches like gene therapy and peptide ther apeutics holds enormous potential for some life threatening anomalies and the combined approach of proteomics, genomics and biotechnology is predicted to empower the most part of the healthcare sector in the upcoming days.